Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jun 4;12(6):576. doi: 10.1038/s41419-021-03803-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 1 — A Expression of miR-21-5p in primary CRC tissues (T) and matched adjacent normal mucosa (N) by ISH (n = 60). Scale bars represent 100 µm. B Expression of miR-21-5p in vessels (indicated by arrows) adjacent to primary CRC tissues and matched adjacent normal mucosa by ISH. Correlation analysis of miR-21-5p expression in colorectal epithelial cells/cancer cells and their adjacent endothelial cells. MiR-21-5p levels were scored as described in “Methods”. Spearman’s correlation coefficient (r) and P-value are shown (n = 60). Scale bars in top panels represent 50 µm. C Correlation analysis of miR-21-5p expression in colorectal epithelial cells/cancer cells and their adjacent microvessel density (labeled by CD31 and indicated by arrows). Microvessel density was scored as described in Methods. Spearman’s correlation coefficient (r) and P-value are shown (n = 60). Scale bars represent 50 µm.