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. 2021 Jun 4;11:11887. doi: 10.1038/s41598-021-91171-w

Table 1.

Characteristics of hospitalized pediatric patients (n = 378).

Overall (n = 378) CKRT (n = 161) Only HD# (n = 145) PD (n = 72) P value*
Sex, n (%) 0.3821
Boy 209 (55.29) 94 (58.39) 80 (55.17) 35(48.61)
Girl 169 (44.71) 67 (41.61) 65 (44.83) 37 (51.39)
Age at index hospitalization, year, n (%)  < 0.0001
 ≤ 1 87 (23.02) 51 (31.68) 3 (2.07) 33 (45.83)
2 to < 3 17 (4.5) 15 (9.32) 2 (1.38) 0
3 to < 8 36 (9.52) 24 (14.91) 8 (5.52) 4 (5.56)
8 to < 13 62 (16.4) 29 (18.01) 24 (16.55) 9 (12.5)
13 to < 18 118 (31.22) 28 (17.39) 73 (50.34) 17 (23.61)
18 to < 20 58 (15.34) 14 (8.7) 35 (24.14) 9 (12.5)
PMCA, CD condition, n (%) 0.0483
Without CD 209 (55.29) 101 (62.73) 66 (45.52) 42 (58.33)
Non-complex CD 18 (4.76) 6 (3.73) 9 (6.21) 3 (4.17)
Complex CD 151 (39.95) 54 (33.54) 70 (48.28) 27 (37.5)
PMCA, organ system, n (%)
Cardiac 64 (16.93) 24 (14.91) 27 (18.62) 13 (18.06) 0.661
Dermatological 1 (0.26) 1 (0.62) 0 (0) 0 (0) 0.5088
Endocrinological 12 (3.17) 5 (3.11) 5 (3.45) 2 (2.78) 0.9633
Gastrointestinal 29 (7.67) 15 (9.32) 12 (8.28) 2 (2.78) 0.2097
Genetic 7 (1.85) 2 (1.24) 3 (2.07) 2 (2.78) 0.7024
Genitourinary 14 (3.7) 2 (1.24) 7 (4.83) 5 (6.94) 0.0683
Hematological 39 (10.32) 15 (9.32) 19 (13.1) 5 (6.94) 0.3205
Immunological 30 (7.94) 9 (5.59) 17 (11.72) 4 (5.56) 0.0993
Malignancy 20 (5.29) 16 (9.94) 3 (2.07) 1 (1.39) 0.0023
Mental health 9 (2.38) 4 (2.48) 4 (2.76) 1 (1.39) 0.8182
Metabolic 23 (6.08) 10 (6.21) 9 (6.21) 4 (5.56) 0.9785
Musculoskeletal 10 (2.65) 2 (1.24) 6 (4.14) 2 (2.78) 0.288
Neurological 31 (8.2) 14 (8.7) 13 (8.97) 4 (5.56) 0.659
Ophthalmological 6 (1.59) 2 (1.24) 3 (2.07) 1 (1.39) 0.8369
Otologic 1 (0.26) 0 (0) 1 (0.69) 0 0.4468
Pulmonary/respiratory 15 (3.97) 10 (6.21) 4 (2.76) 1 (1.39) 0.1395
Renal disease 81 (21.43) 10 (6.21) 50 (34.48) 21 (29.17)  < .0001
Progressive& 139 (36.77) 45 (27.95) 68 (46.9) 26 (36.11) 0.0028
Prior dialysis, n (%) 22 (9.87) 0 20 (18.35) 2 (5.71) 0.0001

CKRT continuous kidney replacement therapy, HD hemodialysis, PD peritoneal dialysis, PMCA pediatric medical complexity algorithm, CD chronic disease.

*P value indicates difference among three dialysis modality groups.

#Some children received more than one dialysis modalities in the index hospitalization. The CKRT group included some patients receiving CKRT + HD; The PD group included some patients receiving PD + HD.

$PMCA and prior dialysis were ascertained among patients with any visits in the study setting 365 days prior to the index hospitalization.

&A progressive condition associated with decreased life expectancy (e.g., muscular dystrophy), malignancy, or continuous technology dependence (e.g., dialysis or tracheostomy).