Table 3.
Deceased (n = 127) | Survivor (n = 251) | aOR (95%CI) P value | |||
---|---|---|---|---|---|
Sex, n (%) | |||||
Boy | 72 (56.69) | 137 (54.58) | 1 | ||
Girl | 55 (43.31) | 114 (45.42) | 0.84 (0.49, 1.46) | 0.5376 | |
Age at index hospitalization, year, n (%) | |||||
≥ 13 | 39 (30.71) | 154 (61.35) | 1 | ||
2–12 | 34 (26.77) | 64 (25.50) | 1.62 | (0.68, 3.85) | 0.2735 |
< 2 | 54 (42.52) | 33 (13.15) | 3.46 | (1.34, 8.93) | 0.0105 |
ECMO, n (%) | |||||
No | 79 (62.20) | 223 (88.84) | 1 | ||
Yes | 48 (37.80) | 28 (11.16) | 1.28 (0.68, 2.41) | 0.4526 | |
AKI defined by, n (%)# | |||||
Diagnosis codes | 20 (15.75) | 50 (19.92) | 1 | ||
Increased SCr | 107 (84.25) | 181 (72.11) | 1.60 (0.77, 3.35) | 0.2077 | |
Diagnosis codes (missing SCr) | 0 | 20 (0.80) | |||
Sum of VIS medication regiment, n (%) | |||||
None | 4 (0.32) | 138 (54.98) | 1 | ||
1–2 | 40 (31.50) | 64 (25.50) | 10.80 (3.51, 33.20) | < .0001 | |
3–4 | 83 (65.35) | 49 (19.52) | 17.10 (5.30, 55.21) | < .0001 | |
Dialysis modality, n (%) | |||||
Only HD | 15 (11.81) | 130 (51.79) | 1 | ||
PD | 88 (69.29) | 73 (29.08) | 1.84 (0.63, 5.38) | 0.2644 | |
CKRT | 24 (18.90) | 48 (19.12) | 2.16 (0.98, 4.76) | 0.0557 | |
eGFR at admission, ml/min/1.73 m2, n (%) | |||||
≥ 60 | 18 (14.17) | 34 (13.55) | 1 | ||
15–60 | 8 (0.06) | 18 (0.07) | 1.02 (0.29, 3.56) | 0.9772 | |
< 15 | 78 (61.42) | 168 (66.93) | 0.33 (0.12, 0.91) | 0.0323 | |
Missing | 23 (18.11) | 31 (12.35) | 0.64 (0.18, 2.29) | 0.4892 | |
PMCA, organ system, n (%) | |||||
Renal disease | |||||
No | 120 (94.49) | 177 (70.52) | 1 | ||
Yes | 7 (0.06) | 74 (29.48) | 0.37 (0.12, 1.13) | 0.0799 | |
Progressive& | |||||
No | 90 (70.87) | 149 (59.36) | 1 | ||
Yes | 37 (29.13) | 102 (40.64) | 1.53 (0.75, 3.11) | 0.2394 |
aOR adjusted odds ratio, EMCO extracorporeal membrane oxygenation, SCr serum creatinine level, VIS vasoactive inotropic score (dopamine dose (mcg/kg/min) + dobutamine dose (mcg/kg/min) + 100 × epinephrine dose (mcg/kg/min) + 10 × milrinone dose (mcg/kg/min) + 10,000 × vasopressin dose (units/kg/min) + 100 × norepinephrine dose (mcg/kg/min), eGFR estimated glomerular filtration rate, PMCA pediatric medical complexity algorithm, CD chronic disease.
#AKI defined by SCr-based criteria during hospital stay or diagnosis codes at hospital discharge with and without (missing) SCr data.
&A progressive condition associated with decreased life expectancy (e.g., muscular dystrophy), malignancy, or continuous technology dependence (e.g., dialysis or tracheostomy).