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. 2021 Jun 4;11:11887. doi: 10.1038/s41598-021-91171-w

Table 3.

Factors associated with mortality among patients receiving dialysis for acute kidney disease (n = 378).

Deceased (n = 127) Survivor (n = 251) aOR (95%CI) P value
Sex, n (%)
Boy 72 (56.69) 137 (54.58) 1
Girl 55 (43.31) 114 (45.42) 0.84 (0.49, 1.46) 0.5376
Age at index hospitalization, year, n (%)
 ≥ 13 39 (30.71) 154 (61.35) 1
2–12 34 (26.77) 64 (25.50) 1.62 (0.68, 3.85) 0.2735
 < 2 54 (42.52) 33 (13.15) 3.46 (1.34, 8.93) 0.0105
ECMO, n (%)
No 79 (62.20) 223 (88.84) 1
Yes 48 (37.80) 28 (11.16) 1.28 (0.68, 2.41) 0.4526
AKI defined by, n (%)#
Diagnosis codes 20 (15.75) 50 (19.92) 1
Increased SCr 107 (84.25) 181 (72.11) 1.60 (0.77, 3.35) 0.2077
Diagnosis codes (missing SCr) 0 20 (0.80)
Sum of VIS medication regiment, n (%)
None 4 (0.32) 138 (54.98) 1
1–2 40 (31.50) 64 (25.50) 10.80 (3.51, 33.20)  < .0001
3–4 83 (65.35) 49 (19.52) 17.10 (5.30, 55.21)  < .0001
Dialysis modality, n (%)
Only HD 15 (11.81) 130 (51.79) 1
PD 88 (69.29) 73 (29.08) 1.84 (0.63, 5.38) 0.2644
CKRT 24 (18.90) 48 (19.12) 2.16 (0.98, 4.76) 0.0557
eGFR at admission, ml/min/1.73 m2, n (%)
 ≥ 60 18 (14.17) 34 (13.55) 1
15–60 8 (0.06) 18 (0.07) 1.02 (0.29, 3.56) 0.9772
 < 15 78 (61.42) 168 (66.93) 0.33 (0.12, 0.91) 0.0323
Missing 23 (18.11) 31 (12.35) 0.64 (0.18, 2.29) 0.4892
PMCA, organ system, n (%)
Renal disease
No 120 (94.49) 177 (70.52) 1
Yes 7 (0.06) 74 (29.48) 0.37 (0.12, 1.13) 0.0799
Progressive&
No 90 (70.87) 149 (59.36) 1
Yes 37 (29.13) 102 (40.64) 1.53 (0.75, 3.11) 0.2394

aOR adjusted odds ratio, EMCO extracorporeal membrane oxygenation, SCr serum creatinine level, VIS vasoactive inotropic score (dopamine dose (mcg/kg/min) + dobutamine dose (mcg/kg/min) + 100 × epinephrine dose (mcg/kg/min) + 10 × milrinone dose (mcg/kg/min) + 10,000 × vasopressin dose (units/kg/min) + 100 × norepinephrine dose (mcg/kg/min), eGFR estimated glomerular filtration rate, PMCA pediatric medical complexity algorithm, CD chronic disease.

#AKI defined by SCr-based criteria during hospital stay or diagnosis codes at hospital discharge with and without (missing) SCr data.

&A progressive condition associated with decreased life expectancy (e.g., muscular dystrophy), malignancy, or continuous technology dependence (e.g., dialysis or tracheostomy).