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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Methods Mol Biol. 2021;2179:385–413. doi: 10.1007/978-1-0716-0779-4_28

Fig. 9.

Fig. 9

The coupling parameters determine the overlap of the stemness window (expression of OCT4 within a range) with the spectrum of EMT-associated phenotypes. The overlap determines which of the phenotypes can acquire stemness. In the top panel, all three phenotypes can acquire stemness. In the middle panel, only epithelial and hybrid E/M phenotypes can acquire stemness. In the bottom panel, only hybrid E/M and mesenchymal phenotypes can acquire stemness