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. 2021 May 18;53(5):788–808. doi: 10.1038/s12276-021-00613-y

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© The Author(s) 2021

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Fig. 2 — Protein arginine methylation is observed in both histones and nonhistone proteins, which contribute to diverse cellular responses for maintaining cellular homeostasis in biological systems. The expression and activity of PRMTs are regulated by developmental and pathogenic processes, genetic mutations, and various environmental factors.