Figure 4:

Tumor contrast to noise ratio (CNR) and signal intensity ratio (SIR) on conventional DWI images and C₁ maps of optimized RSI models. The dashed horizontal line marks the 1:1 tumor:parenchyma CNR or SIR. The upper and lower bounds of each box indicate the interquartile range of CNRs/SIRs from all patients with tumors, while the horizontal line within each box denotes the median CNR/SIR. The whiskers mark the minimum and maximum CNRs/SIRs, excluding any outliers which are marked by a “+”. An asterisk (*) indicates that tumor CNR/SIR is significantly higher on RSI C₁ maps than conventional ADC maps. Double daggers (‡) denotes a significant increase in CNR/SIR compared to the trace DWI images at any b-value. A section mark (§) indicates a significant increase in tumor CNR/SIR compared to the RSI model with one fewer compartment.