FIGURE 1.

Flowchart presenting the analysis of six HE4‐related MRPs in ovarian cancer. First, as shown in the yellow box, through STRING, MCODE, and KEGG enrichment analysis of HE4‐related genes, we screened six MRPs. Second, as shown in the blue box, we performed a comprehensive analysis of mRNA expression, gene variation, and prognosis for these six MRPs. Finally, as shown in the green box, we chose MRPL15 for further verification and mechanism analysis. CNV, copy number variation; GSEA, Gene Set Enrichment Analysis; GTEX, Genotype‐Tissue Expression Portal; HE4, human epididymis protein 4; KEGG, Kyoto Encyclopedia of Genes and Genomes; O, HE4‐High; OV, HE4‐High‐vector; SNV, single‐nucleotide variants; TCGA, The Cancer Genome Atlas