TABLE 5.
Variable | LGA (n = 98) | No LGA (n = 88) | Adjusted OR (95% CI) | P |
---|---|---|---|---|
First trimester | ||||
A1C, mmol/mol | 54.1 ± 1.0 | 50.4 ± 9.5 | 1.04 (1.00–1.08) | 0.02* |
A1C, % | 7.1 ± 1.0 | 6.8 ± 0.9 | — | — |
Mean glucose, mmol/L | 7.9 ± 1.3 | 7.7 ± 1.5 | 1.16 (0.19–1.49) | 0.24 |
SD, mmol/L | 3.2 ± 0.8 | 3.2 ± 0.9 | 1.09 (0.73–1.62) | 0.67 |
Coefficient of variation, % | 40.5 ± 7.2 | 40.6 ± 7.3 | 0.99 (0.95–1.04) | 0.77 |
TIR, %† | 48.2 ± 13.6 | 51.9 ± 14.5 | 0.98 (0.95–1.00) | 0.07 |
TAR, % | 44.8 ± 14.6 | 40.9 ± 16.3 | 1.02 (1.00–1.04) | 0.07 |
TBR, % | 7.0 ± 5.1 | 7.2 ± 5.0 | 0.98 (0.92–1.05) | 0.60 |
Second trimester | ||||
A1C, mmol/mol | 46.4 ± 7.4 | 43.7 ± 8.3 | 1.05 (1.01–1.10) | 0.02* |
A1C, % | 6.4 ± 0.7 | 6.1 ± 0.8 | — | — |
Mean glucose, mmol/L | 7.6 ± 1.0 | 7.1 ± 1.3 | 1.53 (1.12–2.08) | <0.001* |
SD, mmol/L | 2.9 ± 0.6 | 2.7 ± 0.7 | 1.65 (1.00–2.74) | <0.05* |
Coefficient of variation, % | 37.8 ± 5.9 | 37.7 ± 6.7 | 1.00 (0.95–1.06) | 0.93 |
TIR, %† | 51.8 ± 12.3 | 57.9 ± 14.4 | 0.96 (0.94–0.99) | <0.01* |
TAR, % | 41.9 ± 12.8 | 34.0 ± 15.9 | 1.04 (1.02–1.07) | <0.001* |
TBR, % | 6.4 ± 4.5 | 8.0 ± 5.7 | 0.93 (0.87–0.99) | 0.02* |
Third trimester | ||||
A1C, mmol/mol | 47.2 ± 6.7 | 44.0 ± 8.2 | 1.06 (1.02–1.11) | <0.01* |
A1C, % | 6.5 ± 0.6 | 6.2 ± 0.8 | — | — |
Mean glucose, mmol/L | 7.3 ± 1.1 | 6.8 ± 1.1 | 1.57 (1.12–2.19) | <0.001* |
SD, mmol/L | 2.6 ± 0.6 | 2.5 ± 0.6 | 1.60 (0.92–2.77) | 0.09 |
Coefficient of variation, % | 35.9 ± 5.5 | 36.1 ± 6.2 | 0.99 (0.94–1.05) | 0.84 |
TIR, %† | 57.6 ± 12.8 | 62.2 ± 13.4 | 0.97 (0.95–1.00) | 0.04* |
TAR, % | 37.0 ± 13.5 | 30.2 ± 15.3 | 1.03 (1.01–1.06) | <0.01* |
TBR, % | 5.4 ± 4.4 | 7.6 ± 6.4 | 0.92 (0.86–0.98) | <0.01* |
Adjusted for age, smoking status, BMI, and CGM device. Data in LGA and non-LGA columns are mean ± SD.
Statistically significant.
TIR 63–140 mg/dL (3.5–7.8 mmol/L). Adapted from ref. 2.