Table 4.
Differences between groups on standardized neuropsychological domain scores (domain composite z-scores)
| Domains | GRN-bvFTD (n = 18) | bvFTD (n = 18) | AD (n = 18) | P-value | Effect size (ŋ2) |
|---|---|---|---|---|---|
| Attention/Executive Functions/ Initiative/Psychomotor Control | –1.89±0.70 | –1.64±1.01 | –0.99±0.45 | 0.035 | 0.119 |
| Language | –0.81±0.23 | –0.97±0.15 | –0.50±0.34 | 0.107 | 0.015 |
| Memory | –2.22±1.31 | –2.28±1.02 | –2.69±1.00 | 0.021 | 0.16 |
| Calculus | –0.95±0.22 | –0.81±0.44 | –0.90±0.45 | 0.533 | 0.001 |
| Visuoconstructive/Perceptive abilities | –1.47±0.98 | –1.02±0.87 | –1.24±0.67 | 0.032 | 0.444 |
| Orientation | –1.10±0.22 | –0.99±0.37 | –1.23±0.67 | 0.437 | 0.054 |
Data are presented as the mean ± SD. Statistically significant differences between the groups are presented in bold. AD: Alzheimer’s disease; bvFTD: behavioral variant frontotemporal dementia; GRN: progranulin mutation carriers. Group comparisons were performed through non-parametric Kruskal-Wallis analysis.