Table 1.
History of treatment/ current symptoms |
Results |
|
Case No., sex, age (atprimary treatment), nerve, type of injury, time from injury to nerve reconstruction | Before nerve release and ADSC administration / BMRC, VAS, sympathetic reinnervation disorders | Post-surgical revision, nerve release and decompression, scar removal and ADSC administration with microinjections (follow-up – 36 months) |
No. 1, male, 55 yr, median nerve, knife, 1 year | 4 years after injury and 3 years after delayed nerve reconstruction: S0 – Complete sensation loss in fingers I–IV; S0, M5, F1; constant pain in hand VAS 9–10; severe cold intolerance | Sensation recovery in fingers I–IV, (30–45%), S4, 2PD = 6 mm, S4, M5, F5; no pain at rest and during activity VAS 0–1; no cold sensitivity |
No. 2, female, 64 yr, median nerve, knife, 0.5 yr | 4 years after injury and 3.5 years after delayed nerve reconstruction: S0 – Complete sensation loss in fingers I–IV; S0, M4, F1; constant pain in hand VAS 9–10; severe cold intolerance | Sensation recovery in fingers I-IV, (40–50%), S3, 2PD = 10–14 mm; S3, M5, F5; no pain at rest and during activity VAS 0–1; no cold sensitivity |
No. 3, male, 58 yr, median nerve – immediate reconstruction, ulnar nerve – 1 year delayed reconstruction, window | 3 years after injury: S0 – Complete sensation loss in fingers I–V; (median nerve) S0, M4, F4; (ulnar nerve) S0, M4, F4; no pain in hand VAS 0; no cold intolerance | Sensation recovery in fingers I–V, (median nerve) 50%, (ulnar nerve) 30%); S3, 2PD = 10–14 mm; (median nerve) S3, M4, F4, (ulnar nerve) S3, M4, F4; VAS 0; no cold intolerance |
2PD: Two-point discrimination; ADSC: adipose-derived stem cells; BMRC: British Medical Research Council classification; F: functionality; M: motor function; S: sensory function; VAS: Virtual Analogue Scale for pain.