Table 4.
Impact of Awareness of HIE Diagnosis and Treatment Guidelines
| HIE diagnostic indicators, n (%) | HIE diagnosis | P-value | |
| Aware n = 232 (85) | Unaware n = 41 | ||
| Neurological manifestations | 222 (95.7) | 41 (100.0) | 0.366 |
| Arterial Blood gas | 167 (72.0) | 19 (46.3) | 0.001 |
| Abnormal EEG/aEEG | 136 (58.6) | 16 (39.0) | 0.02 |
| Abnormal MRI | 174 (75.0) | 26 (63.4) | 0.122 |
| CT low density shadow | 66 (28.4) | 13 (31.7) | 0.671 |
| Blood neuroenzymatic changes | 75 (32.3) | 11 (26.8) | 0.485 |
| HIE Treatment | |||
| Aware n = 171 (63) | Unaware n = 102 | ||
| Rate of TH, n (%) | 98 (57.3) | 49 (48.0) | 0.137 |
| Neuroprotection agents, n (%) | 133 (77.8) | 89 (87.3) | 0.052 |
| TH Protocol | |||
| Aware n = 129 (88) | Unaware n = 18 | ||
| Rate of TH compliance, n (%) | 37 (28.7) | 2 (11.1) | 0.195 |
Abbreviation: HIE Hypoxic-ischemic encephalopathy, EEG Electroencephalography, aEEG amplitude-integrated electroencephalography, MRI Magnetic resonance imaging, CT Computerized tomography, TH Therapeutic hypothermia