Table 2.
Comparison of risk factors according to asthma outcome in wheezing children
| Variables | Study group (43) | ||
|---|---|---|---|
| Non-asthma | Asthma | p value | |
| Total n(%) | 17(39.5) | 26(60.5) | |
| Sex n(%) | |||
| Male | 10(58.8) | 19(73.1) | 0.329* |
| Female | 7 (41.2) | 7(26.9) | |
| Age group n(%) | |||
| ≤3 years old | 10(58.8) | 11(42.3) | 0.289* |
| 3-5 years old | 7(41.2) | 15(57.7) | |
| Systemic glucocorticoid n(%) | |||
| Yes | 6(35.3) | 4(15.4) | 0.254* |
| No | 11(64.7) | 22(84.6) | |
| Wheezing frequency n(%) | |||
| <4 times | 13(76.5) | 8(30.8) | 0.003* |
| ≥4 times | 4(23.5) | 18(69.2) | |
| Age when first wheezing n(%) | |||
| ≤3 years old | 17(100.0) | 21(80.8) | 0.139* |
| 3-5years old | 0(0.0) | 5(19.2) | |
| Duration of wheezing onset to enroll, median (IQR)(years) | 0.9(0.0,1.5) | 2.1(0.4, 4.8) | 0.052** |
| Allergic rhinitis n(%) | 7(41.2) | 15(57.7) | 0.289* |
| Atopic dermatitis n(%) | 9(52.9) | 17(65.4) | 0.415* |
| Family allergic diseases | 6(35.3) | 17(65.4) | 0.053* |
| Asthma prediction index n(%) | 9(52.9) | 23(88.5) | 0.024*** |
| Inhalant allergen sIgE n(%) | 8(47.1) | 16(69.6) | 0.151* |
| Food allergen sIgE n(%) | 8(47.1) | 15(65.2) | 0.251* |
| Total IgE(IU/ml) | 46(8.6, 204.0) | 192.5(60.9, 805.0) | 0.055** |
|
CD4+CCR6+CRTh2+cells mean±SD(%) |
0.8±0.6 | 1.6±0.8 | <0.001** |
*: Pearson Chi-Square; **: Mann-Whitney Rank sum test; **: t-test; ***: Continuity Correction