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. 2021 Jun 4;14:299. doi: 10.1186/s13071-021-04808-0

Table 5.

Effectiveness of three consecutive monthly doses of Credelio Plus® and afoxolaner + milbemycin oxime based on investigator counts of natural live tick infestations for all tick species on client owned dogs in European field study

Study day Treatment group n Live tick counts % Effectiveness
Range Arithmetic mean
0 Credelio Plus® 147 3–14 4.6
Afoxolaner + Milbemycin oxime 74 3–18 4.2
7 ± 2 Credelio Plus® 145 0–5 0.08 98.2
Afoxolaner + Milbemycin oxime 71 0–1 0.03 99.3
14 ± 2 Credelio Plus® 147 0–1 0.01 99.8
Afoxolaner + Milbemycin oxime 74 0–1 0.01 99.8
21 ± 2 Credelio Plus® 144 0–1 0.01 99.8
Afoxolaner + Milbemycin oxime 73 0–1 0.01 99.8
28 ± 2 Credelio Plus® 147 0–2 0.03 99.3
Afoxolaner + Milbemycin oxime 73 0–1 0.01 99.8
42 ± 2 Credelio Plus® 145 0–0 0 100
Afoxolaner + Milbemycin oxime 72 0–0 0 100
56 ± 2 Credelio Plus® 143 0–0 0 100
Afoxolaner + Milbemycin oxime 72 0–0 0 100
70 ± 2 Credelio Plus® 135 0–0 0 100
Afoxolaner + Milbemycin oxime 72 0–0 0 100
84 ± 2 Credelio Plus® 127 0–0 0 100
Afoxolaner + Milbemycin oxime 65 0–4 0.06 98.6