Table 5.
Effectiveness of three consecutive monthly doses of Credelio Plus® and afoxolaner + milbemycin oxime based on investigator counts of natural live tick infestations for all tick species on client owned dogs in European field study
| Study day | Treatment group | n | Live tick counts | % Effectiveness | |
|---|---|---|---|---|---|
| Range | Arithmetic mean | ||||
| 0 | Credelio Plus® | 147 | 3–14 | 4.6 | – |
| Afoxolaner + Milbemycin oxime | 74 | 3–18 | 4.2 | – | |
| 7 ± 2 | Credelio Plus® | 145 | 0–5 | 0.08 | 98.2 |
| Afoxolaner + Milbemycin oxime | 71 | 0–1 | 0.03 | 99.3 | |
| 14 ± 2 | Credelio Plus® | 147 | 0–1 | 0.01 | 99.8 |
| Afoxolaner + Milbemycin oxime | 74 | 0–1 | 0.01 | 99.8 | |
| 21 ± 2 | Credelio Plus® | 144 | 0–1 | 0.01 | 99.8 |
| Afoxolaner + Milbemycin oxime | 73 | 0–1 | 0.01 | 99.8 | |
| 28 ± 2 | Credelio Plus® | 147 | 0–2 | 0.03 | 99.3 |
| Afoxolaner + Milbemycin oxime | 73 | 0–1 | 0.01 | 99.8 | |
| 42 ± 2 | Credelio Plus® | 145 | 0–0 | 0 | 100 |
| Afoxolaner + Milbemycin oxime | 72 | 0–0 | 0 | 100 | |
| 56 ± 2 | Credelio Plus® | 143 | 0–0 | 0 | 100 |
| Afoxolaner + Milbemycin oxime | 72 | 0–0 | 0 | 100 | |
| 70 ± 2 | Credelio Plus® | 135 | 0–0 | 0 | 100 |
| Afoxolaner + Milbemycin oxime | 72 | 0–0 | 0 | 100 | |
| 84 ± 2 | Credelio Plus® | 127 | 0–0 | 0 | 100 |
| Afoxolaner + Milbemycin oxime | 65 | 0–4 | 0.06 | 98.6 | |