The hydrolysis of maltose catalyzed by MINPs after 24 h at 60 °C in H2Oa.
| Entry | Catalyst | Surfactant | Yield (%) |
|---|---|---|---|
| 1 | MINP(o-G1 + o-7a) | 1a + 2 | 18 ± 2 |
| 2 | MINP(m-G1 + m-7a) | 1a + 2 | 26 ± 4 |
| 3 | MINP(p-G1 + p-7a) | 1a + 2 | 32 ± 4 |
| 4 | MINP(p-G1 + o-7a) | 1a + 2 | 28 ± 4 |
| 5 | MINP(p-G1 + m-7a) | 1a + 2 | 11 ± 2 |
| 6 | MINP(p-G1 + p-7a) | 1b + 2 | 54 ± 7 |
| 7 | MINP(p-G1 + 7b) | 1b + 2 | 17 ± 3 |
| 8 | MINP(p-G1 + 7c) | 1b + 2 | 70 ± 4 |
| 9 | MINP(p-G1 + 7d) | 1b + 2 | 70 ± 8 |
| 10 | MINP(p-G1 + 7e) | 1b + 2 | 31 ± 4 |
| 11 | MINP(p-G1 + 7f) | 1b + 2 | 13 ± 4 |
| 12 | MINP(p-G1 + 7g) | 1b + 2 | 76 ± 4 |
| 13 | MINP(p-G1 + 7h) | 1b + 2 | 82 ± 6 |
| 14 | 7d | — | <1 |
| 15 | NINPb + 7d | 1b + 2 | 0 |
| 16 | None | — | 0 |
a
Reactions were performed in duplicate with 0.2 mM maltose and 20 μM MINP in 1.0 mL of water. Yields were determined via LC-MS using calibration curves generated from authentic samples (Fig. S32).
b
NINP is a nonimprinted nanoparticle prepared without any template or post-modification.