A. The G9a level of rat brain tissues in each group detected by western blot analysis.
	Sham	HI	HI+S	F value	DF
Relative G9a protein level	0.23±0.05	0.82±0.08*	0.56±0.03**	0.58 ± 0.05***	114.7

One-way ANOVA was used to compare the mean difference among the four groups. Tukey’s multiple comparisons test was used for post hoc test.

^*p<0.001 between sham group and HI group,

^**p<0.001 between HI group and HI+S group,

^***p<0.001 between HI group and HI+G group.