A. NRF2 level of cells in each group determined by western blot assay.
	Blank	OGD	OGD+S	OGD+S+NC-siRNA	OGD+S+NRF2-siRNA	F value	DF
Neuronal density ratio	0.83±0.05	0.16±0.04*	0.47±0.07**	0.44±0.03	0.21±0.06***	78.52	4

One-way ANOVA was used to compare the mean difference among the five groups. Tukey’s multiple comparisons test was used for post hoc test,

^*p<0.001 between blank group and OGD group,

^**p<0.001 between OGD group and OGD+S group,

^***p<0.001 between OGD+S group and OGD+S+NRF2-siRNA group.