Fig. 2. Influence of mAb concentration on the 125I-radioiodinationa of aBA-9E7.4 (
) and 9E7.4 (
) and 211At-astatinationb of aBA-9E7.4 (
) and 9E7.4 (
). RCYs determined by radio-ITLC-SG analysis of the crude product. Standard conditions: 30 min, 100 μL, 23 °C, Tris buffer 0.5 M pH 6/DMF (92.5 : 7.5), n ≥ 2. aCu(OTf)2pyr4 (5 mM), 1,10-phenanthroline (5 mM), [125I]NaI (1–5 MBq) bCu(OTf)2pyr4 (2.5 mM), 1,10-phenanthroline (2.5 mM), [211At]NaAt (1–5 MBq).
