Fig. 3. (a) AFM images showing four different sized X-SNA samples synthesized from different linker/SNA ratio. Inserts are corresponding cross-sectional analysis of X-SNA particles. Scale bar = 500 nm. (b) Dynamic light scattering (DLS) and zeta potential measurements of LOX SNA and four different sized X-SNA constructs. (c) Size profile showing increase of linker/SNA ratio leads to increase of the hydrodynamic size. (d) Quantitative correlation of X-SNA sizes measured by DLS and AFM images. Error bars indicate standard deviations of three independent measurements.