Fig. 4.

CD56⁻CD16⁺ NK cells display decreased expression of antiapoptotic proteins. (Left) Expression of antiapoptotic proteins in clusters of CD56^bright, CD56^dimCD16⁻, CD56^dimCD16⁺, and CD56⁻CD16⁺ NK cells was analyzed by manual gating. Differences between clusters were assessed using a Friedman test followed by a Dunn’s test. Comparison between two groups were performed using a Mann–Whitney U test. Red dots indicate AML group 2. Results of 16 representative AML patients are presented as interquartile ranges, median, and whiskers from minimum to maximum. (Right) Marker expression by NK cell subset; blue: CD56^bright NK cells; orange: CD56^dimCD16⁻ NK cells; gray: CD56^dimCD16⁺ NK cells; green: CD56⁻CD16⁺ NK cells. *P < 0.05 and ***P < 0.001; ns, nonsignificant.