Table 2.
Cox regression
| Multivariate HR for OS | Multivariate HR for EFS | |||||
| Variable | HR | 95% CI | P | HR | 95% CI | P |
| Age at diagnosis, years | 1.05 to 1.17 | 0.0003 | 1.06 to 1.03 | 0.0009 | ||
| ≥50 | Reference | Reference | ||||
| <50 | 1.11 | 1.07 | ||||
| ELN | ||||||
| Adverse | Reference | 0.21 to 1.84 | 0.393 | Reference | 0.32 to 2.23 | 0.746 |
| Intermediate | 0.62 | 0.18 to 2.06 | 0.425 | 0.85 | 0.17 to 1.46 | 0.206 |
| Favorable | 0.61 | 0.51 | ||||
| %CD56−CD16+ NK cells | 0.0001 | 1.01 to 1.07 | 0.004 | |||
| Reference | 1.05 to 1.17 | Reference | ||||
| 1.11 | 1.04 | |||||
Multivariate Cox regression models were used to assess the prognostic value of the frequency of CD56−CD16+ NK cells while adjusting for the prognostic factors in the population (age at diagnosis and ELN). ELN, European Leukemia Net genetic classification.