ECCD of chiral bis-phosphine oxides bound to Zn-MAPOL 2.
| Entry | Predicted sign | λ nm, Δε | A/Acorra |
|---|---|---|---|
|
Positive | 427, +416 | +612 |
| 418, −196 | |||
|
Negative | 427, −426 | −654 |
| 418, +228 | |||
|
Negative | 429, −1838 | −3460 |
| 420, +1622 | |||
|
Positive | 429, +332 | +586 |
| 421, −254 | |||
|
Negative | 427, −1646 | −2770 |
| 419, +1124 | |||
|
Positive | 427, +1862 | +3110 |
| 419, −1248 | |||
|
Negative | 427, −1350 | −2154 |
| 418, +804 |
A corresponds to the amplitude for the ECCD spectrum, measured with the addition of 1 equiv. of the bis-phosphine oxide to a 1 μM Zn-MAPOL 2 solution.