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. 2021 Jan 13;12(5):1620–1631. doi: 10.1039/d0sc06412b

In vitro antimicrobial activities (MICs) of metallohelices against Gram-positive and Gram-negative bacteria strains^a.

Compound		MIC/μg mL⁻¹			Ref.
		G-positive		G-negative
		B. subtilis	S. aureus	E. coli
2-Fe(ii)	Racemic	32^a	—	64^e	74
3-Ru(ii)	Racemic	—	>256^b	>256^f	17
3-Co(iii)	Racemic	—	>1024^b	>1024^f	18
9a-Fe(ii)	Λ	2 ^a	8 ^c,d	4 ^g,h	36 and 56
9a-Fe(ii)	Δ	1 ^a	8 ^c,d	8 ^g,h	36 and 56
9b-Fe(ii)	Λ	4 ^a	16 ^d	2 ^h	56
9b-Fe(ii)	Δ	1 ^a	16 ^d	4 ^h	56
9c-Fe(ii)	Λ	8 ^a	16 ^d	64^h	56
9c-Fe(ii)	Δ	4 ^a	16 ^d	32^h	56
9d-Fe(ii)	Λ	2 ^a	2 ^d	16 ^h	56
9d-Fe(ii)	Δ	2 ^a	2 ^d	16 ^h	56
10-Fe(ii)	Λ	—	64^c	32^g	36
10-Fe(ii)	Δ	—	64^c	>128^g	36
11-Fe(ii)	Λ	—	>256^b	>256^f	39
11-Fe(ii)	Δ	—	>256^b	>256^f	39
12-Fe(ii)	Λ	—	>256^b	>256^f	39
12-Fe(ii)	Δ	—	>256^b	>256^f	39
13-Fe(ii)	Λ	—	>128^b	>128^f	38
13-Fe(ii)	Δ	—	>128^b	>128^f	38

^a

Bacterial strains: ^a168, ^bATCC 29213, ^cMRSA252, ^dUSA300, ^eGM2163, ^fATCC 25922, ^gMC4100, ^hTOP10.