Summary of the outcomes of liquid-assisted grinding experiments involving multi-component crystals in the presence of prohibitive liquid additives^a.

Crystal form	Structural changes
	Nitromethane	DMSO	2-Pyrrolidone
(Hvin+)·(Hoxa−), form I	△	○	■
(Hvin+)·(Hoxa−), form II	■	○	■
(thp)·(23diFBA)	○	○	○
(thp)·(26diFBA)	■	○	●
2(thp)·3(ana)	■	○	●
(ibu)·(nic)	■	■	■
(pca)·(oxa)	■	○	●
(caf)·(cou)	■	■	■

^aNo structural change observed: ■, partial or full decomposition into physical mixture of reactants: ○, partial or full decomposition into physical a mixture of a reactant and a new crystal form: ●, polymorphic transformation: △.