Fig. 10. NIR-II probe (Q-NO2) for NTR activity in metastatic breast cancer model. (a) Reaction scheme of Q-NO2 reaction with NTR. (b) Representative images of BL and NIR-II fluorescence signals in luciferase-expressing breast cancer tumours at 0, 8, 16, and 20 days post-implantation. (c) Relative NIR-II fluorescent intensity in mammary fat pads, lymph nodes, and lungs at 0, 8, 16, and 20 days post-implantation normalized to the control. Error bars = S.D. (n = 5). Reproduced from ref. 79 with permission from Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Copyright 2019.
