Fig. 16. ABS probe for PA imaging MMP-2 activity in cancer. (a) Schematic of QC reacting with MMP-2. (b) Representative images of QC irradiated at 680 and 730 nm in different tumour sizes. (c) MMP-2 expression within different tumour sizes determined by western blotting. (d) MMP-2 expression determined by the ratio of PA signal at 680 and 730 nm. Adapted with permission from ref. 115, Copyright 2019 American Chemical Society.
