Probe-modified kinases and binding sites from respective domains detected in TH211-treated Jurkat cells.
| Uniprot | Gene name | Modified sites | Domain name |
|---|---|---|---|
| O95747 | OXSR1 | 229|227| | Protein kinase domain |
| P05771 | PRKCB | 518|515| | Protein kinase domain |
| P05771 | PRKCB | 209| | C2 domain |
| P06239 | LCK | 192|209| | SH2 domain |
| P06239 | LCK | 470|394|441| | Protein kinase domain |
| P06493 | CDK1 | 286|181|270| | Protein kinase domain |
| P16591 | FER | 714| | Protein kinase domain |
| P17252 | PRKCA | 515|512|504| | Protein kinase domain |
| P17252 | PRKCA | 195|232|209| | C2 domain |
| P19367 | HK1 | 346| | Hexokinase domain |
| P19784 | CSNK2A2 | 308| | Protein kinase domain |
| P23743 | DGKA | 240| | Zinc finger phorbol-ester/DAG-type |
| P24941 | CDK2 | 236|237| | Protein kinase domain |
| P27361 | MAPK3 | 280| | Protein kinase domain |
| P28482 | MAPK1 | 263| | Protein kinase domain |
| P36507 | MAP2K2 | 233|187|101| | Protein kinase domain |
| P41240 | CSK | 97| | SH2 domain |
| P41240 | CSK | 67|64| | Src homology 3 (SH3) domain |
| P43403 | ZAP70 | 506|372| | Protein kinase domain |
| P43403 | ZAP70 | 164| | SH2 domain |
| P49840 | GSK3A | 355| | Protein kinase domain |
| P52789 | HK2 | 398|401| | Hexokinase domain |
| P68400 | CSNK2A1 | 307|182| | Protein kinase domain |
| P78527 | PRKDC | 2965|3168|2936|3475| | FAT domain |
| Q00534 | CDK6 | 257|43| | Protein kinase domain |
| Q02750 | MAP2K1 | 97| | Protein kinase domain |
| Q13131 | PRKAA1 | 190|247| | Protein kinase domain |
| Q13153 | PAK1 | 429| | Protein kinase domain |
| Q13177 | PAK2 | 408| | Protein kinase domain |
| Q13555 | CAMK2G | 231| | Protein kinase domain |
| Q15118 | PDK1 | 365| | Histidine kinase core domain |
| Q16539 | MAPK14 | 249|182|103| | Protein kinase domain |
| Q16644 | MAPKAPK3 | 263|76| | Protein kinase domain |
| Q16774 | GUK1 | 53| | Guanylate kinase-like domain |
| Q8NEV1 | CSNK2A3 | 307|182| | Protein kinase domain |
| Q8TBX8 | PIP4K2C | 384| | Phosphatidylinositol phosphate kinase (PIPK) domain |
| Q96KB5 | PBK | 100|74| | Protein kinase domain |
| Q96S44 | TP53RK | 60|67| | Protein kinase domain |
| Q99986 | VRK1 | 194|213|98|113|107|311|188|317|187|147|214|302|314| | Protein kinase domain |