Fig. 6. (a) Illustration of organic fluorophore based wavelength variation for bio-sensing. (b) Schematic of wavelength variation based on a FRET system and the chemical structures of CX-1 and CX-3. (c) The emission spectra of the sensor (CX micelles) upon addition of ONOO−. (d) Ratiometric imaging of a liver during APAP-induced hepatotoxicity with CX micelle administration. Reproduced from ref. 78 with permission from Wiley-VCH, Copyright 2019. (e) Chemical structure of the pH-activatable NIR-II fluorescence sensor BTC1070 and the sensing mechanism. (f) The emission spectra of the sensor (BTC1070) at different pH values. (g) Ratiometric imaging of gastric pH with BTC1070 micelle administration. Reproduced from ref. 79 with permission from Springer Nature, Copyright 2019.
