Benzylic C(sp³)–H acylation of indoles by photoredox/nickel dual catalysis^a.

^aReaction conditions: 1 (0.20 mmol), 4 (0.24 mmol), [Ir] (1.0 mol%), Ni(cod)₂ (5.0 mol%), dtbbpy (7.0 mol%), K₂CO₃ (0.30 mmol), and DMF (0.050 M) irradiated with 34 W blue LEDs. All yields are isolated yields.

^bThe reaction was conducted in the absence of K₂CO₃. [Ir] = Ir(dFCF₃ppy)₂(dtbbpy)PF₆. dtbbpy = 4,4′-di-tert-butyl-2,2′-bipyridine. DMF = N,N-dimethylformamide.