Fig. 4. Condensates composed of different LCDs inhibit Aβ-42 fibril formation. (A) Aggregation profiles of 3.75 μM Aβ-42 solution in the absence (black) and presence of 1 μM, 2 μM, 5 μM and 10 μM Dpb1N-AK-Dpb1N (from left to right). (B) Aggregation profiles of 5 μM Aβ-42 solution in the absence (black) and presence of 1 μM, 5 μM, 10 μM and 20 μM (from left to right) LCD derived from Ddx4. In both panels solid lines represent model simulations that consider a decrease in the effective initial monomer concentration.
