¹²⁹Xe-host interaction parameters obtained from quantitative Hyper-CEST. The free diameter of MOF pores was expanded as the organic length was extended from IRMOF-1 to IRMOF-10. The exchange rate of the ¹²⁹Xe atom in the MOF increased with the expanding MOF pore diameter. The exchange rate of ¹²⁹Xe in the MOF was considerably smaller than that in gas vesicles and larger than that in supermolecular cryptophane-A due to the intermediate pore space for Xe hosting.

Xenon host	Particle diameter/nm	Interior pore diameter for Xe hosting/Å	129Xe exchange rate/s−1
IRMOF-1	106.3	7.93	429 ± 152
IRMOF-8	105.2	9.17	1176 ± 937
IRMOF-10	116.6	12.15	2496 ± 548
Gas vesicle57	519	—	19 300 ± 1800
Cryptophane-a57,58	—	5.4	16 ± 3