Fig. 2. (A) Schematic hemin/G-quadruplex DNAzyme-modified UiO-66 NMOFs catalyzing the oxidation of Amplex Red (2) to the fluorescent resorufin (3). (B) Time-dependent fluorescence changes corresponding to the catalyzed oxidation of Amplex Red (2) to the fluorescent resorufin (3), in the presence of K⁺-ions, hemin and H₂O₂ (curve (i)). Control experiments showing the time-dependent fluorescence changes generated by the (1)-modified NMOFs in the presence of Amplex Red/H₂O₂ and in the absence of K⁺-ions and hemin (curve ii) and the hemin/G-quadruplex-modified NMOFs treated with CE in the presence of K⁺-ions, hemin and Amplex Red/H₂O₂ (curve iii).