Skip to main content
. 2021 Feb 8;12(13):4810–4818. doi: 10.1039/d0sc06744j

Fig. 8. (A) Panel I: amplified CRET-induced detection of p53 by coupling the HCR generating hemin/G-quadruplex polymers to the Fl-loaded NMOFs. Panel II: amplified CRET-induced detection of BRCA1 by coupling the HCR generating hemin/G-quadruplex polymers to the Rh 6G-loaded NMOFs. (B) Panel I: chemiluminescence and CRET-generated fluorescence of Fl upon analyzing various concentrations of p53 by the scheme outlined in (A) panel I: (a) 0 nM; (b) 0.5 nM; (c) 1 nM; (d) 10 nM; (e) 25 nM; (f) 333 nM. Panel II: calibration curve corresponding to the CRET-generated fluorescence of Fl in the presence of variable concentrations of p53. (C) Panel I: chemiluminescence and CRET-generated fluorescence of Rh 6G upon analyzing various concentrations of BRCA1 by the scheme outlined in (A) panel II: (a) 0 nM; (b) 5 nM; (c) 33 nM; (d) 100 nM; (e) 333 nM. Panel II: calibration curve corresponding to the CRET-generated fluorescence of Rh 6G in the presence of variable concentrations of BRCA1. Error bars derived from N = 3 experiments.

Fig. 8