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Fig. 4. (A) 64Cu-LDH-BSA schematic representation, autoradiographic images of TLC plates of chelator-free labeled-64Cu LDH for 1 h, with a labeling yield of LDH, LDH-BSA and BSA after chelator-free labeling with 64Cu at different reaction times calculated from autoradiography images of TLC plates and (B) post-injection, time-dependent PET images for 64Cu-LDH-BSA and 64Cu-BSA on 4T1 tumor-bearing mice. Strong tumor signals observed in the mice post-injection with 64Cu-LDH-BSA.134 Reproduced from ref. 134 with permission from Nature Publishing Group, copyright 2015.