Table 2.

Univariate and Multivariate Cox Regression Analyses of Clinicopathologic Factors with Recurrence-Free Survival in the Training Set

	Univariate Analysis		Multivariate Analysis
	HR (95% CI)	p	HR (95% CI)	p
Sex		0.161		0.144
Female	Reference		Reference
Male	0.644 (0.349–1.191)		0.627 (0.335–1.174)
Age, years
<20	1.363 (0.369–5.039)	0.642	–	–
20–49	1.680 (0.511–5.519)	0.393	–	–
≥50	Reference		–	–
Position		–		–
Maxilla	–		–
Mandible	–		–
Laterality
Left	1.694 (0.656–4.375)	0.277	–	–
Right	1.367 (0.670–3.407)	0.503	–	–
Bilateral	Reference		–	–
Site characteristics		0.316		–
Anterior	Reference		–
Posterior	1.615 (0.633–4.118)		–
Size, cm		0.862		–
<5	0.945 (0.499–1.791)		–
≥5	Reference		–
Symptom		0.434		–
Pain	Reference		–
Painless	1.318 (0.660–2.631)		–
Duration of symptom, months		0.314		–
<12	1.464 (0.698–3.074)		–
≥12	Reference		–
Numbness of lower lip		0.787		–
Yes	0.822 (0.198–3.411)		–
No	Reference		–
Radiographic features
Multilocular	Reference		Reference
Unilocular	0.583 (0.304–1.118)	0.104	0.791 (0.365–1.715)	0.553
Others	0.700 (0.210–2.332)	0.561	0.866 (0.257–2.919)	0.816
Cortical bone perforation		0.023*
Yes	5.242 (1.262–21.77)		4.257 (1.007–18.008)	0.049*
No	Reference		Reference
Root(s) resorption		0.012*		0.044*
Yes	12.74 (1.751–92.72)		7.786 (1.053–57.582)
No	Reference		Reference
Impacted tooth involvement		0.427		–
Yes	1.284 (0.693–2.38)		–
No	Reference		–
Pathological type
Unicystic	0.435 (0.119–1.593)	0.209	–	–
Follicular	0.654 (0.155–2.762)	0.564	–	–
Plexiform	0.870 (0.259–2.924)	0.822	–	–
Others	0.911 (0.093–8.868)	0.936	–	–
Desmoplastic	Reference		–	–
WHO classification		0.076		0.041*
Unicystic	0.520 (0.255–1.062)		0.398 (0.164–0.964)
Conventional	Reference		Reference
Treatment pattern		0.004**		<0.001***
Curettage	4.519 (1.603–12.74)		7.526 (2.570–22.037)
Radical treatment	Reference		Reference

Notes: *p < 0.05, **p < 0.01, ***p < 0.001.

Abbreviations: HR, hazards ratio; CI, confidence interval.