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. 2021 Jun 1;15:2339–2355. doi: 10.2147/DDDT.S288011

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© 2021 Zhao et al.

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CA exhibits protective effects in T1DM mice. (A and B) Effects of CA on the body weight (A) and fasting glucose levels (B) of normal and T1DM mice. (C) Glucose tolerance test and (D) insulin resistance were measured in normal mice and T1DM mice treated with vehicle or CA. (E) PAS analysis of glycogen synthesis in the liver tissues from mice and T1DM mice treated with vehicle or CA. (F) H&E staining of the heart tissues from normal mice and T1DM mice treated with vehicle or CA. (G) Masson staining of the heart tissues from normal mice and T1DM mice treated with vehicle or CA. N = 6. *P<0.05.

Abbreviations: CA, cinnamaldehyde; T1DM, type 1 diabetes mellitus.