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. 2021 May 29;2021:1765220. doi: 10.1155/2021/1765220

Table 2.

A summary of the MDS-UPDRS limitations [4, 9, 10].

Accuracy unknown How to track comorbidities does not exist
Subjective, nonlinear Low internal consistency computed
Ordinal scale with score meaning, level, differences, and divisions unknown Need for testing scale for responsivity to change over time
Scores cannot differentiate nor compare patients Can be affected by prior patient activities, but not recorded
All score sections reported, but what do they mean? Completed in a limited timeframe (clinic visit)
No connection to clinical stages Questions difficult to read and understand
Only native English-speaking rated and patients participated in initial testing Responses based on interpretation by rater and patient
Not enough participants in any other racial or ethnic group in evaluation (other than non-Latino Caucasians) Respondents may not answer appropriately, fear of score outcome, lower total scores
Effects of age, gender, race, and ethnicity on ratings have not been examined Based on physician's experience, inexperience
Need for non-English scale translations Nonmotor symptoms not clinically diagnosed
Interrater reliability needs to be established Cannot be used as a severity measure of any behavior