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. 2021 Apr 29;12(6):1613–1630. doi: 10.1007/s13300-021-01050-w

Table 1.

American Diabetes Association treatment goals and guidance [14]

Treatment targets ADA Guidance
A1C

• A1C goal for many nonpregnant adults is < 7% (53 mmol/mol)

• More stringent A1C goals (such as < 6.5% [48 mmol/mol]) for some patients, but care should be taken to avoid significant hypoglycemia or polypharmacy (e.g., in patients with a short duration of diabetes, T2D treated with lifestyle or metformin only, long life expectancy, or no significant CVD)

• Less stringent A1C goals (e.g., < 8% [64 mmol/mol]) may be appropriate for some patients (e.g., those with a history of severe hypoglycemia, limited life expectancy, advanced micro- or macrovascular complications, extensive comorbid conditions, or long-standing diabetes in whom the goal is difficult to achieve)

• Reassess glycemic targets over time

BP

• BP control should be optimized to reduce the risk or slow the progression of CKD

• BP targets should be individualized through a shared decision-making process

• Patients with hypertension should, at a minimum, be treated to BP targets of < 140/90 mmHg to reduce CVD mortality and slow CKD progression

• Lower BP targets (e.g., < 130/80 mmHg) should be considered for some patients based on individual anticipated benefits and risks (e.g., those with ≥ 300 mg/day albuminuria)

A1C Glycated hemoglobin, ADA American Diabetes Association, BP blood pressure, CKD chronic kidney disease, CVD cardiovascular disease, T2D type 2 diabetes