Table 1.

Whole patient cohort and lymphopenic vs non-lymphopenic patients

Patients	Whole cohort (n = 1034)	Normal ALC (n = 836)	Lymphopenia = 198	p value
Female sex [n (%)]	723 (69.9)	569 (68.1)	154 (77.8)	0.007
Age, years	38.8 (10.2)	38.0 (10.1)	42.1 (10.1)	< 0.001
Time since first symptom, years	9.5 (8.0)	9.4 (7.9)	9.9 (8.2)	0.407
EDSS score	1.94 (1.5)	1.94 (1.5)	1.92 (1.4)	0.862
Treatment naïves [n (%)]	318 (30.8%)	263 (31.5)	55 (27.8)	0.313
No. of relapses in previous year	0.56 (0.7)	0.54 (0.7)	0.61 (0.8)	0.218
No. of Gd + lesions	0.68 (1.3)	0.67 (1.2)	0.73 (1.4)	0.542

EDSS Expanded Disability Status Score, ALC Absolute lymphocyte count, Gd + gadolinium-enhancing lesion

All values are reported as mean (standard deviation) unless indicated otherwise

In bold are reported significant difference at a two-sided α level < 0.05