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. 2021 Jan 23;268(6):2175–2184. doi: 10.1007/s00415-020-10373-w

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© The Author(s) 2021

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Fig. 2 — CSF KIF5A levels are elevated in progressive MS in the Cardiff cohort. KIF5A protein expression in cerebrospinal fluid samples were detected using ELISA. There was a significant increase in KIF5A expression in progressive MS cases (n = 10) compared with RRMS (n = 63) but not CIS (n = 26). Values represented as mean ± SEM. Statistical test used: one-way ANOVA with post-hoc Bonferroni; **p < 0.01. CIS clinically isolated syndrome, KIF5A kinesin superfamily motor protein 5A, RRMS relapsing–remitting multiple sclerosis