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. 2021 Jan 23;268(6):2175–2184. doi: 10.1007/s00415-020-10373-w

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© The Author(s) 2021

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Fig. 7 — DMT incidence within MS susceptibility genotype subgroups in the Cardiff cohort (n = 88). A higher percentage of patients heterozygous (AG) or homozygous (AA) for MS risk SNPs rs703842 (χ² = 20.69, p < 0.001; a) and rs12368653 (χ² = 19.31, p < 0.001; b) received DMT compared to those without (GG). Statistical test used: Chi-square test, ***p < 0.001. AA homozygous adenine, AG heterozygous adenine/guanine, DMT disease-modifying therapy, GG homozygous guanine