Table 3.

Multivariate analysis of IIH sample storage and MS cohort variables on KIF5A expression in the Bristol cohort

a
Protein	n	Variables	Coefficient	Standard error	t	p value	95% Confidence intervals
KIF5A (ng/mL)	96	IIH vs RRMS	0.040	0.017	− 2.33	0.022	0.006	0.074
		IIH vs progressive MS	0.076	0.025	3.03	0.003	0.026	0.125
		RRMS vs progressive MS	0.036	0.027	1.34	0.184	− 0.017	0.088
		IIH and MS storage time	0.004	0.003	1.13	0.260	− 0.003	0.011

b
Protein	n	Variables	Coefficient	Standard error	t	p value	95% confidence intervals
KIF5A (ng/mL)	47	MS storage time	0.006	0.004	1.47	0.150	− 0.002	0.015
		MS age	− 0.001	0.001	− 0.74	0.462	− 0.003	0.001
		MS sex	− 0.021	0.029	− 0.72	0.477	− 0.078	0.037

Bonferroni correction to the required αλπηα 0.05 cut-off for significance has been applied. Significant associations highlighted in bold

IIH idiopathic intracranial hypertension, KIF kinesin superfamily motor protein, MS multiple sclerosis, RRMS relapsing–remitting multiple sclerosis