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. 2021 Jun 5;7:135. doi: 10.1038/s41420-021-00520-1

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — A Heat-map of PGK1 gene expression from the TCGA RNA sequence database in nontumor and tumor tissues derived from clinical patients with lung cancer. B Kaplan–Meier analysis of PGK1 RNA expression at concurrently low or high levels by in-silico analysis at the endpoint of overall survival probability in TCGA lung cancer patients (p = 1.1e-15, p = 2.5e-10, respectively). C Heat-map of PGK1 gene expression from the TCGA RNA sequence database in nontumor and tumor tissues derived from clinical patients with lung adenocarcinoma. D Kaplan–Meier analysis of PGK1 RNA expression at concurrently low or high levels by in-silico analysis at the endpoint of overall survival probability in TCGA lung adenocarcinoma patients (p = 5.3e-08, p = 2e-14, respectively). E Heat-map of PGK1 gene expression from the TCGA RNA sequence database in nontumor and tumor tissues derived from clinical patients with lung squamous carcinoma. F Kaplan–Meier analysis of PGK1 RNA expression at concurrently low or high levels by in-silico analysis at the endpoint of overall survival probability in TCGA lung squamous carcinoma patients (p = 0.98, p = 0.88, respectively).