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. 2021 Jun 5;7:135. doi: 10.1038/s41420-021-00520-1

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — A PGK1 and HTATSF1 protein expression in the paired normal and tumor tissues derived from clinical lung cancer patients. Statistical significance was analyzed by a paired t-test. Scale bar: 400 μm. B IHC staining for the PGK1 protein. The intensity of IHC staining was scored as a range from 0 to 3. Scale bar: 50 μm. C Quantification of HTATSF1 expression by immunohistochemistry analysis of lung cancer specimens by each corresponding clinical parameter. D PGK1 protein expression in several tumor tissues derived from clinical lung cancer patients. Scale bar: 400 μm. 20x: 200μm.E Kaplan–Meier analysis of the overall survival and disease-free survival probabilities of clinical lung cancer patients according to the intensity (low = 0 and 1, high = 2 and 3) of IHC staining for the PGK1 protein combined with the HTATSF1 protein level.