Table 1.
Clinical relevance of PGK1 expression in lung cancer.
Characteristics | PGK1 expression, n (%) | |||
---|---|---|---|---|
n | Low (n = 59) |
High (n = 48) |
P value | |
Age | ||||
<65 y ≧65 y |
56 51 |
31(55.4) 28(54.9) |
25(44.6) 23(45.1) |
0.558 |
Sex | ||||
Male | 48 | 30(62.5) | 18(37.5) | 0.118 |
Female | 59 | 29(49.2) | 30(50.8) | |
Smoking status | ||||
No | 40 | 22(55.0) | 18(45.0) | 0.570 |
Yes | 67 | 37(55.2) | 30(44.8) | |
Histological type | ||||
Adenocarcinoma | 65 | 35(53.8) | 30(46.2) | 0.669 |
Squamous carcinoma | 35 | 19(54.3) | 16(45.7) | |
Large cell carcinoma | 7 | 5(71.4) | 2(28.6) | |
Stagea | ||||
I + II | 46 | 30(65.2) | 12(30.0) | 0.052 |
III + IV | 61 | 29(47.5) | 26(46.4) | |
Tumor status | ||||
T1 + T2 | 75 | 41(54.7) | 34(45.3) | 0.526 |
T3 + T4 | 32 | 18(56.3) | 14(43.7) | |
Lymph node status | ||||
N0 | 38 | 27(71.1) | 11(28.9) | 0.012* |
N1-3 | 69 | 32(46.4) | 37(53.6) | |
Distal metastasis status | ||||
M0 | 79 | 45(57.0) | 34(43.0) | 0.338 |
M1 | 28 | 14(50.0) | 14(50.0) |
SD standard deviation.
*p value < 0.05 was considered statistically significant (Student’s t test for continuous variables and Pearson’s chi-square test for variables).
aThe tumor stage, tumor, lymph node, and distal metastasis status were classified according to the international system for staging lung cancer.