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. 2021 May 6;2021(5):CD013623. doi: 10.1002/14651858.CD013623.pub2

Summary of findings 6. Reactive gel surfaces compared with reactive air surfaces for preventing pressure ulcers.

Reactive gel surfaces compared with reactive air surfaces for preventing pressure ulcers
Patient or population: preventing pressure ulcers
Setting: nursing home
Intervention: reactive gel surfaces
Comparison: reactive air surfaces
Outcomes Anticipated absolute effects* (95% CI) Relative effect
(95% CI) № of participants
(studies) Certainty of the evidence
(GRADE) Comments
Risk with reactive air surfaces Risk with reactive gel surfaces
Proportion of participants developing a new pressure ulcer
Follow‐up: 6 months Study population RR 0.80
(0.36 to 1.77) 66
(1 RCT) ⊕⊝⊝⊝
Very lowa,b It is uncertain if there is a difference in the proportion of participants developing a new ulcer between reactive gel surfaces and reactive air surfaces.
303 per 1,000 242 per 1,000
(109 to 536)
Time to pressure ulcer incidence The included study did not report this outcome.
Support surface‐associated patient comfort The included study did not report this outcome.
All reported adverse events The included study did not report this outcome.
Health‐related quality of life The included study did not report this outcome.
Cost effectiveness The included study did not report this outcome.
*The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).

CI: Confidence interval; RR: Risk ratio
GRADE Working Group grades of evidenceHigh certainty: we are very confident that the true effect lies close to that of the estimate of the effect.
Moderate certainty: we are moderately confident in the effect estimate; the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different.
Low certainty: our confidence in the effect estimate is limited; the true effect may be substantially different from the estimate of the effect.
Very low certainty: we have very little confidence in the effect estimate; the true effect is likely to be substantially different from the estimate of effect.

aDowngraded once for unclear overall risk of bias.
bDowngraded twice for imprecision because the OIS was not met and the very wide confidence interval crossed RRs = 0.75 and 1.25.