Table 2.
Echocardiographic characteristics of the study population, stratified by outcome
| Variables | Total | Event-free group (n = 21) | Adverse cardiac event group (n = 20) | p-value |
|---|---|---|---|---|
| LVEF, % | 25 (20, 34) | 30 (25, 35) | 21 (19, 23) | < 0.01 |
| LV GLS, % | -8.1 ± 3.72 | -9.9 ± 2.8 | -6.2 ± 3.7 | < 0.001 |
| E/GLS [× 102], cm/s | -8.9 (-18.0, -6.3) | -8.1 (-9.8, -5.8) | -14.8 (-25.6, -8.6) | < 0.01 |
| LVEDD, cm | 6.8 ± 0.8 | 6.6 ± 0.7 | 7.1 ± 0.9 | 0.06 |
| LAVi, ml/m2 | 66 (50, 77) | 55 (53, 76) | 73 (46, 81) | 0.63 |
| Mitral DT, ms | 164 (127, 194) | 145 (111, 187) | 142 (98, 187) | 0.29 |
| Mitral E/A | 2.1 (0.9, 2.9) | 2 (0.8, 2.7) | 2.4 (1.2, 3.3) | 0.44 |
| Average E/e’ | 14.2 (12.3, 15.6) | 13.7 (10.9, 15.1) | 15.0 (13.1, 17.4) | 0.13 |
| Functional mitral regurgitation ≥ moderate, n (%) | 24 (58) | 11 (52) | 13 (65) | 0.41 |
| Functional tricuspid regurgitation ≥ moderate, n (%) | 16 (39) | 6 (29) | 10 (50) | 0.16 |
| RV end-diastolic diameter, cm | 3.3 (3, 3.6) | 3.2 (3.0, 3.5) | 3.5 (3.1, 3.7) | 0.08 |
| Severely impaired RV systolic function, n (%) | 13 (32) | 5 (24) | 8 (40) | 0.27 |
| TR systolic jet velocity (m/s) | 2.7 (2.5, 3.2) | 2.5 (2.4, 2.7) | 2.8 (2.5, 3.0) | 0.16 |
Values are expressed as: mean ± SD, median (25th percentile, 75th percentile) or n (%)
DT deceleration time, E/A ratio of early-diastolic LV inflow velocity (E) to atrial-systolic velocity (A), E/e’ ratio of early-diastolic LV inflow velocity (E) to early-diastolic mitral annular velocity (e´), E/GLS ratio of early-diastolic LV inflow velocity (E) to global longitudinal strain (GLS), GLS global longitudinal strain, LAVi left atrial indexed volume, LVEDD left ventricular end-diastolic diameter, LVEF left ventricular ejection fraction, TR tricuspid regurgitation