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. 2021 Jun 5;26:24. doi: 10.1186/s11658-021-00265-w

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Regulatory effects of RAP2A overexpression on PDAC cell proliferation, migration and invasions. A Transfection of pcDNA3.1-RAP2A or pcDNA3.1 was performed in SW1990 and PANC-1 cells. After that, the protein expression level of RAP2A was measured by western blot analysis. B Changes in proliferation of transfected SW1990 and PANC-1 cells were evaluated by CCK-8 assay. C, D Cell migration and invasion were analyzed in transfected SW1990 and PANC-1 cells. **p < 0.01, ***p < 0.001 vs. pcDNA3.1 group