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. 2021 Jun 5;26:24. doi: 10.1186/s11658-021-00265-w

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — RAP2A reintroduction attenuated the effects of miR-33a-5p overexpression. SW1990 and PANC-1 cells were co-transfected with the miR-33a-5p mimics and either pcDNA3.1-RAP2A or pcDNA3.1. A RAP2A protein expression was determined using western blot analysis in the aforementioned cells. The transfected cells were subjected to the CCK-8 assay (B), Transwell migration (C) and invasion (D) assays, respectively. **p < 0.01, ***p < 0.001 vs. the miR-NC + pcDNA3.1 group