Table 4.
Presence of carbapenemase* and Mrc1 genes in isolates by organism, Thailand, 2016–2018
| n (% of isolates by organism) | P value€ | ||||||
|---|---|---|---|---|---|---|---|
| Carbapenemase Gene | Total (N = 3946) |
Organisms | |||||
|
Klebsiella pneumoniae (N = 2659) |
Escherichia coli (N = 799) |
Enterobacter cloacae (N = 113) |
Citrobacter freundii (N = 12) |
Other (N = 102) |
|||
| NDM | 2501 (63) | 1577 (55) | 776 (94) | 736 (59) | 11 (100) | 64 (65) | < .0001 |
| OX-48-like | 1892 (48) | 1703 (59) | 149 (18) | 27 (22) | 1 (9) | 12 (12) | < .0001 |
| IMP | 97 (2) | 46 (2) | 1 (< 1) | 31 (25) | 0 (0) | 19 (19) | < .0001 |
| No CP Gene | 102 (3) | 74 (3) | 9 (1) | 18 (16) | 0 (0) | 1 (1) | < .0001 |
| Mcr1 | 10 (< 1) | 5 (< 1) | 5 (1) | 0 (0) | 0 (0) | 0 (0) | 0.23 |
*Not mutually exclusive: 634 had NDM and OXA and 7 had IMP and OXA, 5 had NDM and IMP, 6 Mcr1 and NDM, 3 Mcr1 and OXA-48-like
*No VIM or KPC
€p-value using chi-square or fisher exact test to compare presence of carbapenemase genes and MCR-1 across organisms