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. 2021 Jun 5;21:279. doi: 10.1186/s12872-021-02078-3

Table 3.

Multivariable Cox proportional hazard for six-month death

Clinical variables Six-month death
HR 95% CI P value
D-dimer 1.11 1.05, 1.18 < .001
RHD 1.60 0.80, 3.18 .183
CHD 0.79 0.39, 1.58 0.497
Prosthetic valve 2.68 1.27, 5.68 .010
NYHA III-IV 4.50 2.57, 7.88 < .001
SCr > 2 mg/dL 0.89 0.40, 1.95 .765
Vegetation > 10 mm 2.85 1.46, 5.55 .002
Blood culture +  0.55 0.33, 0.94 .027
PVC 1.40 0.66, 2.97 0.379
No surgery 7.84 4.15, 14.79 < 0.001

HR, hazard ratio; RHD, rheumatic heart disease; CHD, congenital heart disease, NYHA, New-York Heart Association; LVEF, left ventricular ejection fraction; PVC, perivalvular complications (refer to echocardiographic findings of perivalvular leak or abscess); SCr, serum creatinine